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Membrane Permeabilization Induced by Sphingosine: Effect of Negatively Charged Lipids

Sphingosine [(2S, 3R, 4E)-2-amino-4-octadecen-1, 3-diol] is the most common sphingoid long chain base in sphingolipids. It is the precursor of important cell signaling molecules, such as ceramides. In the last decade it has been shown to act itself as a potent metabolic signaling molecule, by activa...

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Main Authors: Jiménez-Rojo, Noemi, Sot, Jesús, Viguera, Ana R., Collado, M. Isabel, Torrecillas, Alejandro, Gómez-Fernández, J.C., Goñi, Félix M., Alonso, Alicia
Formato: Artigo
Idioma:Inglês
Publicado: The Biophysical Society 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4070072/
https://ncbi.nlm.nih.gov/pubmed/24940775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2014.04.038
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