Caricamento...

Mechanisms of Action and Reduced Cardiotoxicity of Pixantrone; a Topoisomerase II Targeting Agent with Cellular Selectivity for the Topoisomerase IIα Isoform

Pixantrone is a new noncardiotoxic aza-anthracenedione anticancer drug structurally related to anthracyclines and anthracenediones, such as doxorubicin and mitoxantrone. Pixantrone is approved in the European Union for the treatment of relapsed or refractory aggressive B cell non-Hodgkin lymphoma. T...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:J Pharmacol Exp Ther
Autori principali: Hasinoff, Brian B., Wu, Xing, Patel, Daywin, Kanagasabai, Ragu, Karmahapatra, Soumendrakrishna, Yalowich, Jack C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Pharmacology and Experimental Therapeutics 2016
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4746493/
https://ncbi.nlm.nih.gov/pubmed/26660439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.115.228650
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !