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Peripheral Adenosine A(3) Receptor Activation Causes Regulated Hypothermia in Mice That Is Dependent on Central Histamine H(1) Receptors

Adenosine can induce hypothermia, as previously demonstrated for adenosine A(1) receptor (A(1)AR) agonists. Here we use the potent, specific A(3)AR agonists MRS5698, MRS5841, and MRS5980 to show that adenosine also induces hypothermia via the A(3)AR. The hypothermic effect of A(3)AR agonists is inde...

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書目詳細資料
發表在:J Pharmacol Exp Ther
Main Authors: Carlin, Jesse Lea, Tosh, Dilip K., Xiao, Cuiying, Piñol, Ramón A., Chen, Zhoumou, Salvemini, Daniela, Gavrilova, Oksana, Jacobson, Kenneth A., Reitman, Marc L.
格式: Artigo
語言:Inglês
出版: The American Society for Pharmacology and Experimental Therapeutics 2016
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4746492/
https://ncbi.nlm.nih.gov/pubmed/26606937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.115.229872
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