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Activation of neuronal adenosine A(1) receptors causes hypothermia through central and peripheral mechanisms
Extracellular adenosine, a danger signal, can cause hypothermia. We generated mice lacking neuronal adenosine A(1) receptors (A(1)AR, encoded by the Adora1 gene) to examine the contribution of these receptors to hypothermia. Intracerebroventricular injection of the selective A(1)AR agonist (Cl-ENBA,...
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| Publié dans: | PLoS One |
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| Auteurs principaux: | , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Public Library of Science
2020
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7743955/ https://ncbi.nlm.nih.gov/pubmed/33326493 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0243986 |
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