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Activation of neuronal adenosine A(1) receptors causes hypothermia through central and peripheral mechanisms

Extracellular adenosine, a danger signal, can cause hypothermia. We generated mice lacking neuronal adenosine A(1) receptors (A(1)AR, encoded by the Adora1 gene) to examine the contribution of these receptors to hypothermia. Intracerebroventricular injection of the selective A(1)AR agonist (Cl-ENBA,...

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Detaylı Bibliyografya
Yayımlandı:PLoS One
Asıl Yazarlar: Province, Haley S., Xiao, Cuiying, Mogul, Allison S., Sahoo, Ankita, Jacobson, Kenneth A., Piñol, Ramón A., Gavrilova, Oksana, Reitman, Marc L.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2020
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7743955/
https://ncbi.nlm.nih.gov/pubmed/33326493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0243986
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