Peripheral Adenosine A(3) Receptor Activation Causes Regulated Hypothermia in Mice That Is Dependent on Central Histamine H(1) Receptors

Adenosine can induce hypothermia, as previously demonstrated for adenosine A(1) receptor (A(1)AR) agonists. Here we use the potent, specific A(3)AR agonists MRS5698, MRS5841, and MRS5980 to show that adenosine also induces hypothermia via the A(3)AR. The hypothermic effect of A(3)AR agonists is inde...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Pharmacol Exp Ther
Egile Nagusiak: Carlin, Jesse Lea, Tosh, Dilip K., Xiao, Cuiying, Piñol, Ramón A., Chen, Zhoumou, Salvemini, Daniela, Gavrilova, Oksana, Jacobson, Kenneth A., Reitman, Marc L.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The American Society for Pharmacology and Experimental Therapeutics 2016
Gaiak:
Endocrine and Diabetes
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4746492/
https://ncbi.nlm.nih.gov/pubmed/26606937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.115.229872
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