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Peripheral Adenosine A(3) Receptor Activation Causes Regulated Hypothermia in Mice That Is Dependent on Central Histamine H(1) Receptors
Adenosine can induce hypothermia, as previously demonstrated for adenosine A(1) receptor (A(1)AR) agonists. Here we use the potent, specific A(3)AR agonists MRS5698, MRS5841, and MRS5980 to show that adenosine also induces hypothermia via the A(3)AR. The hypothermic effect of A(3)AR agonists is inde...
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| Veröffentlicht in: | J Pharmacol Exp Ther |
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| Hauptverfasser: | , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The American Society for Pharmacology and Experimental Therapeutics
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4746492/ https://ncbi.nlm.nih.gov/pubmed/26606937 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.115.229872 |
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