Structure of the poly-C9 component of the complement membrane attack complex

The membrane attack complex (MAC)/perforin-like protein complement component 9 (C9) is the major component of the MAC, a multi-protein complex that forms pores in the membrane of target pathogens. In contrast to homologous proteins such as perforin and the cholesterol-dependent cytolysins (CDCs), al...

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Veröffentlicht in:Nat Commun
Hauptverfasser: Dudkina, Natalya V., Spicer, Bradley A., Reboul, Cyril F., Conroy, Paul J., Lukoyanova, Natalya, Elmlund, Hans, Law, Ruby H. P., Ekkel, Susan M., Kondos, Stephanie C., Goode, Robert J. A., Ramm, Georg, Whisstock, James C., Saibil, Helen R., Dunstone, Michelle A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4742998/
https://ncbi.nlm.nih.gov/pubmed/26841934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms10588
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