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Conformational Changes during Pore Formation by the Perforin-Related Protein Pleurotolysin

Membrane attack complex/perforin-like (MACPF) proteins comprise the largest superfamily of pore-forming proteins, playing crucial roles in immunity and pathogenesis. Soluble monomers assemble into large transmembrane pores via conformational transitions that remain to be structurally and mechanistic...

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שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:PLoS Biol
Main Authors: Lukoyanova, Natalya, Kondos, Stephanie C., Farabella, Irene, Law, Ruby H. P., Reboul, Cyril F., Caradoc-Davies, Tom T., Spicer, Bradley A., Kleifeld, Oded, Traore, Daouda A. K., Ekkel, Susan M., Voskoboinik, Ilia, Trapani, Joseph A., Hatfaludi, Tamas, Oliver, Katherine, Hotze, Eileen M., Tweten, Rodney K., Whisstock, James C., Topf, Maya, Saibil, Helen R., Dunstone, Michelle A.
פורמט: Artigo
שפה:Inglês
יצא לאור: Public Library of Science 2015
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4318580/
https://ncbi.nlm.nih.gov/pubmed/25654333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1002049
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