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Reversal of the Transcriptome by Prostaglandin E(2) during Myofibroblast Dedifferentiation

Myofibroblasts, the major effector cells in pathologic fibrosis, derive from the differentiation of fibroblasts driven by mediators such as transforming growth factor-β1 (TGF-β1) and biomechanical signals. Although the myofibroblast has traditionally been considered a terminally differentiated cell,...

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Detalhes bibliográficos
Publicado no:Am J Respir Cell Mol Biol
Main Authors: Wettlaufer, Scott H., Scott, Jacob P., McEachin, Richard C., Peters-Golden, Marc, Huang, Steven K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4742926/
https://ncbi.nlm.nih.gov/pubmed/26098591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2014-0468OC
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