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Prostaglandin E(2) Inhibits Specific Lung Fibroblast Functions via Selective Actions of PKA and Epac-1

Via their capacities for proliferation and synthesis of matrix proteins such as collagen, fibroblasts are key effectors in the pathogenesis of fibrotic disorders such as idiopathic pulmonary fibrosis. Prostaglandin E(2) (PGE(2)) potently inhibits these functions in lung fibroblasts through receptor...

詳細記述

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書誌詳細
主要な著者: Huang, Steven K., Wettlaufer, Scott H., Chung, Jooho, Peters-Golden, Marc
フォーマット: Artigo
言語:Inglês
出版事項: American Thoracic Society 2008
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2551707/
https://ncbi.nlm.nih.gov/pubmed/18421013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2008-0080OC
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