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Prostaglandin E(2) Inhibits Specific Lung Fibroblast Functions via Selective Actions of PKA and Epac-1
Via their capacities for proliferation and synthesis of matrix proteins such as collagen, fibroblasts are key effectors in the pathogenesis of fibrotic disorders such as idiopathic pulmonary fibrosis. Prostaglandin E(2) (PGE(2)) potently inhibits these functions in lung fibroblasts through receptor...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Thoracic Society
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2551707/ https://ncbi.nlm.nih.gov/pubmed/18421013 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2008-0080OC |
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