Prostaglandin E(2) induces fibroblast apoptosis by modulating multiple survival pathways

Although the lipid mediator prostaglandin E(2) (PGE(2)) exerts antifibrotic effects by inhibiting multiple fibroblast functions, its ability to regulate fibroblast survival is unknown. Here, we examined the effects of this prostanoid on apoptosis and apoptosis pathways in normal and fibrotic lung fi...

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Библиографические подробности
Главные авторы: Huang, Steven K., White, Eric S., Wettlaufer, Scott H., Grifka, Heather, Hogaboam, Cory M., Thannickal, Victor J., Horowitz, Jeffrey C., Peters-Golden, Marc
Формат: Artigo
Язык:Inglês
Опубликовано: The Federation of American Societies for Experimental Biology 2009
Предметы:
Research Communications
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2812040/
https://ncbi.nlm.nih.gov/pubmed/19671668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.08-128801
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