Prostaglandin E(2) induces fibroblast apoptosis by modulating multiple survival pathways

Although the lipid mediator prostaglandin E(2) (PGE(2)) exerts antifibrotic effects by inhibiting multiple fibroblast functions, its ability to regulate fibroblast survival is unknown. Here, we examined the effects of this prostanoid on apoptosis and apoptosis pathways in normal and fibrotic lung fi...

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Detalhes bibliográficos
Main Authors: Huang, Steven K., White, Eric S., Wettlaufer, Scott H., Grifka, Heather, Hogaboam, Cory M., Thannickal, Victor J., Horowitz, Jeffrey C., Peters-Golden, Marc
Formato: Artigo
Idioma:Inglês
Publicado em: The Federation of American Societies for Experimental Biology 2009
Assuntos:
Research Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2812040/
https://ncbi.nlm.nih.gov/pubmed/19671668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.08-128801
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