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Reversal of Myofibroblast Differentiation by Prostaglandin E(2)

Differentiation of fibroblasts into α-smooth muscle actin (SMA)–expressing myofibroblasts represents a critical step in the pathogenesis of fibrotic disorders, and is generally regarded as irreversible. Prostaglandin E(2) (PGE(2)) has been shown to prevent multiple aspects of fibroblast activation,...

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Detalhes bibliográficos
Main Authors: Garrison, Garth, Huang, Steven K., Okunishi, Katsuhide, Scott, Jacob P., Kumar Penke, Loka Raghu, Scruggs, Anne M., Peters-Golden, Marc
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3707380/
https://ncbi.nlm.nih.gov/pubmed/23470625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2012-0262OC
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