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Reversal of Myofibroblast Differentiation by Prostaglandin E(2)
Differentiation of fibroblasts into α-smooth muscle actin (SMA)–expressing myofibroblasts represents a critical step in the pathogenesis of fibrotic disorders, and is generally regarded as irreversible. Prostaglandin E(2) (PGE(2)) has been shown to prevent multiple aspects of fibroblast activation,...
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Main Authors: | , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Thoracic Society
2013
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3707380/ https://ncbi.nlm.nih.gov/pubmed/23470625 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2012-0262OC |
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