Učitavanje...

SMAC mimetic Debio 1143 synergizes with taxanes, topoisomerase inhibitors and bromodomain inhibitors to impede growth of lung adenocarcinoma cells

Targeting anti-apoptotic proteins can sensitize tumor cells to conventional chemotherapies or other targeted agents. Antagonizing the Inhibitor of Apoptosis Proteins (IAPs) with mimetics of the pro-apoptotic protein SMAC is one such approach. We used sensitization compound screening to uncover possi...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Izdano u:Oncotarget
Glavni autori: Langdon, Casey G., Wiedemann, Norbert, Held, Matthew A., Mamillapalli, Ramanaiah, Iyidogan, Pinar, Theodosakis, Nicholas, Platt, James T., Levy, Frederic, Vuagniaux, Gregoire, Wang, Shaomeng, Bosenberg, Marcus W., Stern, David F.
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4741938/
https://ncbi.nlm.nih.gov/pubmed/26485762
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!