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Debio 1143, an antagonist of multiple inhibitor-of-apoptosis proteins, activates apoptosis and enhances radiosensitization of non-small cell lung cancer cells in vitro

Inhibitors of apoptosis (IAPs) limit the effectiveness of radiation in non-small cell lung cancer (NSCLC). Debio 1143 (D1143) is an antagonist of IAPs. The purpose of this study was to investigate the potential of D1143 as a radiosensitizer in NSCLC. MTS assays were performed in two NSCLC cell lines...

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Bibliografiske detaljer
Udgivet i:Am J Cancer Res
Main Authors: Liu, Ningbo, Tao, Zhen, Blanc, Justin M Le, Zaorsky, Nicholas G, Sun, Yunguang, Vuagniaux, Grégoire, Dicker, Adam P, Lu, Bo
Format: Artigo
Sprog:Inglês
Udgivet: e-Century Publishing Corporation 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4266726/
https://ncbi.nlm.nih.gov/pubmed/25520882
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