DEBIO 1143, an IAP inhibitor, reverses carboplatin resistance in ovarian cancer cells and triggers apoptotic or necroptotic cell death

The poor prognosis of ovarian cancer (it is the leading cause of death from gynecological cancers) is mainly due to the acquisition of resistance to carboplatin. Among the possible resistance pathways, resistance to apoptosis and especially the overexpression of inhibitor of apoptosis proteins (IAP)...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Thibault, Benoît, Genre, Ludivine, Le Naour, Augustin, Broca, Clothilde, Mery, Eliane, Vuagniaux, Grégoire, Delord, Jean Pierre, Wiedemann, Norbert, Couderc, Bettina
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6294826/
https://ncbi.nlm.nih.gov/pubmed/30552344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-35860-z
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados