The inhibitor apoptosis protein antagonist Debio 1143 Is an attractive HIV-1 latency reversal candidate

Antiretroviral therapy (ART) suppresses HIV replication, but does not cure the infection because replication-competent virus persists within latently infected CD4+ T cells throughout years of therapy. These reservoirs contain integrated HIV-1 genomes and can resupply active virus. Thus, the developm...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Bobardt, Michael, Kuo, Joseph, Chatterji, Udayan, Chanda, Sumit, Little, Susan J., Wiedemann, Norbert, Vuagniaux, Gregoire, Gallay, Philippe A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6361451/
https://ncbi.nlm.nih.gov/pubmed/30716099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0211746
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