Systematic Exploration of Active Site Mutations on Human Deoxycytidine Kinase Substrate Specificity

Por Iyidogan, Pinar, Lutz, Stefan
Publicado em 2008

Understanding the molecular mechanism of sequence dependent Tenofovir removal by HIV-1 reverse transcriptase: differences in primer binding site versus polypurine tract

Por Iyidogan, Pinar, Anderson, Karen S.
Publicado em 2012

Recent findings on the mechanisms involved in tenofovir resistance

Por Iyidogan, Pinar, Anderson, Karen S
Publicado em 2014

Current Perspectives on HIV-1 Antiretroviral Drug Resistance

Por Iyidogan, Pinar, Anderson, Karen S.
Publicado em 2014

Design, Synthesis, and Antiviral Evaluation of Chimeric Inhibitors of HIV Reverse Transcriptase

Por Iyidogan, Pinar, Sullivan, Todd J., Chordia, Mahendra D., Frey, Kathleen M., Anderson, Karen S.
Publicado em 2013

Bifunctional Inhibition of Human Immunodeficiency Virus Type 1 Reverse Transcriptase: Mechanism and Proof-of-Concept as a Novel Therapeutic Design Strategy

Por Bailey, Christopher M., Sullivan, Todd J., Iyidogan, Pinar, Tirado-Rives, Julian, Chung, Raymond, Ruiz-Caro, Juliana, Mohamed, Ebrahim, Jorgensen, William, Hunter, Roger, Anderson, Karen S.
Publicado em 2013

A nanotherapy strategy significantly enhances anticryptosporidial activity of an inhibitor of bifunctional thymidylate synthase-dihydrofolate reductase from Cryptosporidium

Por Mukerjee, Anindita, Iyidogan, Pinar, Castellanos-Gonzalez, Alejandro, Cisneros, José A., Czyzyk, Daniel, Ranjan, Amalendu Prakash, Jorgensen, William L., White, A. Clinton, Vishwanatha, Jamboor K., Anderson, Karen S.
Publicado no Bioorg Med Chem Lett (2015)

The Broad Spectrum Receptor Tyrosine Kinase Inhibitor Dovitinib Suppresses Growth of BRAF Mutant Melanoma Cells in Combination with Other Signaling Pathway Inhibitors

Por Langdon, Casey G., Held, Matthew A., Platt, James T., Meeth, Katrina, Iyidogan, Pinar, Mamillapalli, Ramanaiah, Koo, Andrew B., Klein, Michael, Liu, Zongzhi, Bosenberg, Marcus W., Stern, David F.
Publicado no Pigment Cell Melanoma Res (2015)

SMAC mimetic Debio 1143 synergizes with taxanes, topoisomerase inhibitors and bromodomain inhibitors to impede growth of lung adenocarcinoma cells

Por Langdon, Casey G., Wiedemann, Norbert, Held, Matthew A., Mamillapalli, Ramanaiah, Iyidogan, Pinar, Theodosakis, Nicholas, Platt, James T., Levy, Frederic, Vuagniaux, Gregoire, Wang, Shaomeng, Bosenberg, Marcus W., Stern, David F.
Publicado no Oncotarget (2015)

Bifunctional Inhibition of HIV-1 Reverse Transcriptase: A First Step in Designing a Bifunctional Triphosphate()

Por Piao, Dongyuan, Basavapathruni, Aravind, Iyidogan, Pinar, Dai, Guangxiu, Hinz, Wolfgang, Ray, Adrian S., Murakami, Eisuke, Feng, Joy Y., You, Fei, Dutschman, Ginger E., Austin, David J., Parker, Kathlyn A., Anderson, Karen S.
Publicado em 2012