Arsenic trioxide disrupts glioma stem cells via promoting PML degradation to inhibit tumor growth

Glioblastoma multiforme (GBM) is the most lethal brain tumor. Tumor relapse in GBM is inevitable despite maximal therapeutic interventions. Glioma stem cells (GSCs) have been found to be critical players in therapeutic resistance and tumor recurrence. Therapeutic drugs targeting GSCs may significant...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Zhou, Wenchao, Cheng, Lin, Shi, Yu, Ke, Susan Q., Huang, Zhi, Fang, Xiaoguang, Chu, Cheng-wei, Xie, Qi, Bian, Xiu-wu, Rich, Jeremy N., Bao, Shideng
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4741931/
https://ncbi.nlm.nih.gov/pubmed/26510911
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