Requirement of PML SUMO Interacting Motif for RNF4- or Arsenic Trioxide-Induced Degradation of Nuclear PML Isoforms

PML, the organizer of nuclear bodies (NBs), is expressed in several isoforms designated PMLI to VII which differ in their C-terminal region due to alternative splicing of a single gene. This variability is important for the function of the different PML isoforms. PML NB formation requires the covale...

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Main Authors: Maroui, Mohamed Ali, Kheddache-Atmane, Sabrina, El Asmi, Faten, Dianoux, Laurent, Aubry, Muriel, Chelbi-Alix, Mounira K.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3445614/
https://ncbi.nlm.nih.gov/pubmed/23028697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0044949
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