Role of SUMO in RNF4-mediated Promyelocytic Leukemia Protein (PML) Degradation: Sumoylation of pml and phospho-switch control of its sumo binding domain dissected in living cells([Image: see text])

Promyelocytic leukemia protein (PML) is a tumor suppressor acting as the organizer of subnuclear structures called PML nuclear bodies (NBs). Both covalent modification of PML by the small ubiquitin-like modifier (SUMO) and non-covalent binding of SUMO to the PML SUMO binding domain (SBD) are necessa...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Hoofdauteurs: Percherancier, Yann, Germain-Desprez, Delphine, Galisson, Frédéric, Mascle, Xavier H., Dianoux, Laurent, Estephan, Patricia, Chelbi-Alix, Mounira K., Aubry, Muriel
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Biochemistry and Molecular Biology 2009
Onderwerpen:
Protein Synthesis, Post-Translational Modification, and Degradation
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2713554/
https://ncbi.nlm.nih.gov/pubmed/19380586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.006387
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items