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Arsenic trioxide disrupts glioma stem cells via promoting PML degradation to inhibit tumor growth

Glioblastoma multiforme (GBM) is the most lethal brain tumor. Tumor relapse in GBM is inevitable despite maximal therapeutic interventions. Glioma stem cells (GSCs) have been found to be critical players in therapeutic resistance and tumor recurrence. Therapeutic drugs targeting GSCs may significant...

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Bibliografische gegevens
Gepubliceerd in:Oncotarget
Hoofdauteurs: Zhou, Wenchao, Cheng, Lin, Shi, Yu, Ke, Susan Q., Huang, Zhi, Fang, Xiaoguang, Chu, Cheng-wei, Xie, Qi, Bian, Xiu-wu, Rich, Jeremy N., Bao, Shideng
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Impact Journals LLC 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4741931/
https://ncbi.nlm.nih.gov/pubmed/26510911
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