CDK1 phosphorylation of TAZ in mitosis inhibits its oncogenic activity

The transcriptional co-activator with PDZ-binding motif (TAZ) is a downstream effector of the Hippo tumor suppressor pathway, which plays important roles in cancer and stem cell biology. Hippo signaling inactivates TAZ through phosphorylation (mainly at S89). In the current study, we define a new la...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Oncotarget
Egile Nagusiak: Zhang, Lin, Chen, Xingcheng, Stauffer, Seth, Yang, Shuping, Chen, Yuanhong, Dong, Jixin
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Impact Journals LLC 2015
Gaiak:
Research Paper
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4741614/
https://ncbi.nlm.nih.gov/pubmed/26375055
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