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MST2 Phosphorylation at Serine 385 in Mitosis Inhibits its Tumor Suppressing Activity
Mammalian sterile 20-like kinase 1/2 (MST1/2) are core tumor suppressors in the Hippo signaling pathway. MST1/2 have been shown to regulate mitotic progression. Here, we report a novel mechanism for phospho-regulation of MST2 in mitosis and its biological significance in cancer. We found that the mi...
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| Vydáno v: | Cell Signal |
|---|---|
| Hlavní autoři: | , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2016
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5067232/ https://ncbi.nlm.nih.gov/pubmed/27566175 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2016.08.013 |
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