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Ajuba Phosphorylation by CDK1 Promotes Cell Proliferation and Tumorigenesis

Recent studies identified the adaptor protein Ajuba as a positive regulator of Yes-associated protein (YAP) oncogenic activity through inhibiting large tumor suppressor (Lats1/2) core kinases of the Hippo pathway, a signaling pathway that plays important roles in cancer. In this study, we define a n...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Chen, Xingcheng, Stauffer, Seth, Chen, Yuanhong, Dong, Jixin
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4938193/
https://ncbi.nlm.nih.gov/pubmed/27226586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.722751
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