Arenobufagin intercalates with DNA leading to G(2) cell cycle arrest via ATM/ATR pathway

Arenobufagin, a representative bufadienolide, is the major active component in the traditional Chinese medicine Chan'su. It possesses significant antineoplastic activity in vitro. Although bufadienolide has been found to disrupt the cell cycle, the underlying mechanisms of this disruption are n...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:Oncotarget
Main Authors: Deng, Li-Juan, Peng, Qun-Long, Wang, Long-Hai, Xu, Jun, Liu, Jun-Shan, Li, Ying-Jie, Zhuo, Zhen-Jian, Bai, Liang-Liang, Hu, Li-Ping, Chen, Wei-Min, Ye, Wen-Cai, Zhang, Dong-Mei
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2015
Teme:
Research Paper
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4741450/
https://ncbi.nlm.nih.gov/pubmed/26485758
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki