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Arenobufagin intercalates with DNA leading to G(2) cell cycle arrest via ATM/ATR pathway
Arenobufagin, a representative bufadienolide, is the major active component in the traditional Chinese medicine Chan'su. It possesses significant antineoplastic activity in vitro. Although bufadienolide has been found to disrupt the cell cycle, the underlying mechanisms of this disruption are n...
保存先:
出版年: | Oncotarget |
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主要な著者: | , , , , , , , , , , , |
フォーマット: | Artigo |
言語: | Inglês |
出版事項: |
Impact Journals LLC
2015
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主題: | |
オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4741450/ https://ncbi.nlm.nih.gov/pubmed/26485758 |
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