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Arenobufagin intercalates with DNA leading to G(2) cell cycle arrest via ATM/ATR pathway

Arenobufagin, a representative bufadienolide, is the major active component in the traditional Chinese medicine Chan'su. It possesses significant antineoplastic activity in vitro. Although bufadienolide has been found to disrupt the cell cycle, the underlying mechanisms of this disruption are n...

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保存先:
書誌詳細
出版年:Oncotarget
主要な著者: Deng, Li-Juan, Peng, Qun-Long, Wang, Long-Hai, Xu, Jun, Liu, Jun-Shan, Li, Ying-Jie, Zhuo, Zhen-Jian, Bai, Liang-Liang, Hu, Li-Ping, Chen, Wei-Min, Ye, Wen-Cai, Zhang, Dong-Mei
フォーマット: Artigo
言語:Inglês
出版事項: Impact Journals LLC 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4741450/
https://ncbi.nlm.nih.gov/pubmed/26485758
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