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Galiellalactone induces cell cycle arrest and apoptosis through the ATM/ATR pathway in prostate cancer cells
Galiellalactone (GL) is a fungal metabolite that presents antitumor activities on prostate cancer in vitro and in vivo. In this study we show that GL induced cell cycle arrest in G(2)/M phase, caspase-dependent apoptosis and also affected the microtubule organization and migration ability in DU145 c...
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| Publicado no: | Oncotarget |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Impact Journals LLC
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4826221/ https://ncbi.nlm.nih.gov/pubmed/26683224 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.6606 |
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