Galiellalactone induces cell cycle arrest and apoptosis through the ATM/ATR pathway in prostate cancer cells

Galiellalactone (GL) is a fungal metabolite that presents antitumor activities on prostate cancer in vitro and in vivo. In this study we show that GL induced cell cycle arrest in G(2)/M phase, caspase-dependent apoptosis and also affected the microtubule organization and migration ability in DU145 c...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Oncotarget
Egile Nagusiak: García, Víctor, Lara-Chica, Maribel, Cantarero, Irene, Sterner, Olov, Calzado, Marco A., Muñoz, Eduardo
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Impact Journals LLC 2015
Gaiak:
Research Paper
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4826221/
https://ncbi.nlm.nih.gov/pubmed/26683224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.6606
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