Measure transcript integrity using RNA-seq data

BACKGROUND: Stored biological samples with pathology information and medical records are invaluable resources for translational medical research. However, RNAs extracted from the archived clinical tissues are often substantially degraded. RNA degradation distorts the RNA-seq read coverage in a gene-...

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Detalhes bibliográficos
Publicado no:BMC Bioinformatics
Main Authors: Wang, Liguo, Nie, Jinfu, Sicotte, Hugues, Li, Ying, Eckel-Passow, Jeanette E., Dasari, Surendra, Vedell, Peter T., Barman, Poulami, Wang, Liewei, Weinshiboum, Richard, Jen, Jin, Huang, Haojie, Kohli, Manish, Kocher, Jean-Pierre A.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Methodology Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4739097/
https://ncbi.nlm.nih.gov/pubmed/26842848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-016-0922-z
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