Mutational Landscapes of Sequential Prostate Metastases and Matched Patient Derived Xenografts during Enzalutamide Therapy

Developing patient derived models from individual tumors that capture the biological heterogeneity and mutation landscape in advanced prostate cancer is challenging, but essential for understanding tumor progression and delivery of personalized therapy in metastatic castrate resistant prostate cance...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Kohli, Manish, Wang, Liguo, Xie, Fang, Sicotte, Hugues, Yin, Ping, Dehm, Scott M., Hart, Steven N., Vedell, Peter T., Barman, Poulami, Qin, Rui, Mahoney, Douglas W., Carlson, Rachel E., Eckel-Passow, Jeanette E., Atwell, Thomas D., Eiken, Patrick W., McMenomy, Brendan P., Wieben, Eric D., Jha, Gautam, Jimenez, Rafael E., Weinshilboum, Richard, Wang, Liewei
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4687867/
https://ncbi.nlm.nih.gov/pubmed/26695660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0145176
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