Mutational Landscapes of Sequential Prostate Metastases and Matched Patient Derived Xenografts during Enzalutamide Therapy

Developing patient derived models from individual tumors that capture the biological heterogeneity and mutation landscape in advanced prostate cancer is challenging, but essential for understanding tumor progression and delivery of personalized therapy in metastatic castrate resistant prostate cance...

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Opis bibliograficzny
Wydane w:PLoS One
Główni autorzy: Kohli, Manish, Wang, Liguo, Xie, Fang, Sicotte, Hugues, Yin, Ping, Dehm, Scott M., Hart, Steven N., Vedell, Peter T., Barman, Poulami, Qin, Rui, Mahoney, Douglas W., Carlson, Rachel E., Eckel-Passow, Jeanette E., Atwell, Thomas D., Eiken, Patrick W., McMenomy, Brendan P., Wieben, Eric D., Jha, Gautam, Jimenez, Rafael E., Weinshilboum, Richard, Wang, Liewei
Format: Artigo
Język:Inglês
Wydane: Public Library of Science 2015
Hasła przedmiotowe:
Research Article
Dostęp online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4687867/
https://ncbi.nlm.nih.gov/pubmed/26695660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0145176
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