Measure transcript integrity using RNA-seq data

BACKGROUND: Stored biological samples with pathology information and medical records are invaluable resources for translational medical research. However, RNAs extracted from the archived clinical tissues are often substantially degraded. RNA degradation distorts the RNA-seq read coverage in a gene-...

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Vydáno v:BMC Bioinformatics
Hlavní autoři: Wang, Liguo, Nie, Jinfu, Sicotte, Hugues, Li, Ying, Eckel-Passow, Jeanette E., Dasari, Surendra, Vedell, Peter T., Barman, Poulami, Wang, Liewei, Weinshiboum, Richard, Jen, Jin, Huang, Haojie, Kohli, Manish, Kocher, Jean-Pierre A.
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2016
Témata:
Methodology Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4739097/
https://ncbi.nlm.nih.gov/pubmed/26842848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-016-0922-z
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