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Reversible interconversion and maintenance of mammary epithelial cell characteristics by the ligand-regulated EGFR system
Epithelial cell plasticity is controlled by extracellular cues, but the underlying mechanisms remain to be fully understood. Epidermal growth factor (EGF) and amphiregulin (AREG) are high- and low-affinity ligands for EGF receptor (EGFR), respectively. EGFR signaling is known to promote epithelial-m...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4735799/ https://ncbi.nlm.nih.gov/pubmed/26831618 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep20209 |
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