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Actin filament dynamics impacts keratinocyte stem cell maintenance

Cultured human epidermal keratinocyte stem cells (holoclones) are crucial for regenerative medicine for burns and genetic disorders. In serial culture, holoclones progressively lose their proliferative capacity to become transient amplifying cells with limited growth (paraclones), a phenomenon terme...

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Detalhes bibliográficos
Main Authors: Nanba, Daisuke, Toki, Fujio, Matsushita, Natsuki, Matsushita, Sachi, Higashiyama, Shigeki, Barrandon, Yann
Formato: Artigo
Idioma:Inglês
Publicado em: WILEY-VCH Verlag 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3628097/
https://ncbi.nlm.nih.gov/pubmed/23554171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/emmm.201201839
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