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Actin filament dynamics impacts keratinocyte stem cell maintenance

Cultured human epidermal keratinocyte stem cells (holoclones) are crucial for regenerative medicine for burns and genetic disorders. In serial culture, holoclones progressively lose their proliferative capacity to become transient amplifying cells with limited growth (paraclones), a phenomenon terme...

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Bibliografiske detaljer
Main Authors: Nanba, Daisuke, Toki, Fujio, Matsushita, Natsuki, Matsushita, Sachi, Higashiyama, Shigeki, Barrandon, Yann
Format: Artigo
Sprog:Inglês
Udgivet: WILEY-VCH Verlag 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3628097/
https://ncbi.nlm.nih.gov/pubmed/23554171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/emmm.201201839
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