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Cell surface annexins regulate ADAM-mediated ectodomain shedding of proamphiregulin

A disintegrin and metalloproteinase (ADAM) is a family of enzymes involved in ectodomain shedding of various membrane proteins. However, the molecular mechanism underlying substrate recognition by ADAMs remains unknown. In this study, we successfully captured and analyzed cell surface transient asse...

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Detalhes bibliográficos
Main Authors: Nakayama, Hironao, Fukuda, Shinji, Inoue, Hirofumi, Nishida-Fukuda, Hisayo, Shirakata, Yuji, Hashimoto, Koji, Higashiyama, Shigeki
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3350559/
https://ncbi.nlm.nih.gov/pubmed/22438584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E11-08-0683
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