Ectodomain Shedding of Lymphatic Vessel Endothelial Hyaluronan Receptor 1 (LYVE-1) Is Induced by Vascular Endothelial Growth Factor A (VEGF-A)

Lymphatic vessel endothelial hyaluronan receptor 1 (LYVE-1), a type I transmembrane glycoprotein, is known as one of the most specific lymphatic vessel markers in the skin. In this study, we found that the ectodomain of LYVE-1 undergoes proteolytic cleavage, and this process produces soluble LYVE-1....

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Nishida-Fukuda, Hisayo, Araki, Ryoichi, Shudou, Masachika, Okazaki, Hidenori, Tomono, Yasuko, Nakayama, Hironao, Fukuda, Shinji, Sakaue, Tomohisa, Shirakata, Yuji, Sayama, Koji, Hashimoto, Koji, Detmar, Michael, Higashiyama, Shigeki, Hirakawa, Satoshi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4865900/
https://ncbi.nlm.nih.gov/pubmed/26966180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.683201
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