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Cell surface annexins regulate ADAM-mediated ectodomain shedding of proamphiregulin

A disintegrin and metalloproteinase (ADAM) is a family of enzymes involved in ectodomain shedding of various membrane proteins. However, the molecular mechanism underlying substrate recognition by ADAMs remains unknown. In this study, we successfully captured and analyzed cell surface transient asse...

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Bibliografiske detaljer
Main Authors: Nakayama, Hironao, Fukuda, Shinji, Inoue, Hirofumi, Nishida-Fukuda, Hisayo, Shirakata, Yuji, Hashimoto, Koji, Higashiyama, Shigeki
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Cell Biology 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3350559/
https://ncbi.nlm.nih.gov/pubmed/22438584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E11-08-0683
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