PET Imaging Evaluation of [(18)F]DBT-10, a Novel Radioligand Specific to α(7) Nicotinic Acetylcholine Receptors, in Nonhuman Primates

PURPOSE: PET radioligands specific to α(7) nicotinic acetylcholine receptors (nAChRs) afford in vivo imaging of this receptor for neuropathologies such as Alzheimer’s disease, schizophrenia, and substance abuse. This work aims to characterize the kinetic properties of an α(7)-nAChR specific radiolig...

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Detalhes bibliográficos
Publicado no:Eur J Nucl Med Mol Imaging
Main Authors: Hillmer, Ansel T., Zheng, Ming-Qiang, Li, Songye, Scheunemann, Matthias, Lin, Shu-fei, Holden, Daniel, Labaree, David, Ropchan, Jim, Teodoro, Rodrigo, Deuther-Conrad, Winnie, Carson, Richard E., Brust, Peter, Huang, Yiyun
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4733418/
https://ncbi.nlm.nih.gov/pubmed/26455500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00259-015-3209-0
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