PET Imaging Evaluation of [(18)F]DBT-10, a Novel Radioligand Specific to α(7) Nicotinic Acetylcholine Receptors, in Nonhuman Primates

PURPOSE: PET radioligands specific to α(7) nicotinic acetylcholine receptors (nAChRs) afford in vivo imaging of this receptor for neuropathologies such as Alzheimer’s disease, schizophrenia, and substance abuse. This work aims to characterize the kinetic properties of an α(7)-nAChR specific radiolig...

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Détails bibliographiques
Publié dans:Eur J Nucl Med Mol Imaging
Auteurs principaux: Hillmer, Ansel T., Zheng, Ming-Qiang, Li, Songye, Scheunemann, Matthias, Lin, Shu-fei, Holden, Daniel, Labaree, David, Ropchan, Jim, Teodoro, Rodrigo, Deuther-Conrad, Winnie, Carson, Richard E., Brust, Peter, Huang, Yiyun
Format: Artigo
Langue:Inglês
Publié: 2015
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4733418/
https://ncbi.nlm.nih.gov/pubmed/26455500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00259-015-3209-0
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