PET Imaging Evaluation of [(18)F]DBT-10, a Novel Radioligand Specific to α(7) Nicotinic Acetylcholine Receptors, in Nonhuman Primates

PURPOSE: PET radioligands specific to α(7) nicotinic acetylcholine receptors (nAChRs) afford in vivo imaging of this receptor for neuropathologies such as Alzheimer’s disease, schizophrenia, and substance abuse. This work aims to characterize the kinetic properties of an α(7)-nAChR specific radiolig...

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Bibliografske podrobnosti
izdano v:Eur J Nucl Med Mol Imaging
Main Authors: Hillmer, Ansel T., Zheng, Ming-Qiang, Li, Songye, Scheunemann, Matthias, Lin, Shu-fei, Holden, Daniel, Labaree, David, Ropchan, Jim, Teodoro, Rodrigo, Deuther-Conrad, Winnie, Carson, Richard E., Brust, Peter, Huang, Yiyun
Format: Artigo
Jezik:Inglês
Izdano: 2015
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4733418/
https://ncbi.nlm.nih.gov/pubmed/26455500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00259-015-3209-0
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