SIRT1 Limits Adipocyte Hyperplasia through c-Myc Inhibition

The expansion of fat mass in the obese state is due to increased adipocyte hypertrophy and hyperplasia. The molecular mechanism that drives adipocyte hyperplasia remains unknown. The NAD(+)-dependent protein deacetylase sirtuin 1 (SIRT1), a key regulator of mammalian metabolism, maintains proper met...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:J Biol Chem
Päätekijät: Abdesselem, Houari, Madani, Aisha, Hani, Ahmad, Al-Noubi, Muna, Goswami, Neha, Ben Hamidane, Hisham, Billing, Anja M., Pasquier, Jennifer, Bonkowski, Michael S., Halabi, Najeeb, Dalloul, Rajaa, Sheriff, Mohamed Z., Mesaeli, Nasrin, ElRayess, Mohamed, Sinclair, David A., Graumann, Johannes, Mazloum, Nayef A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Biochemistry and Molecular Biology 2016
Aiheet:
Cell Biology
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4732199/
https://ncbi.nlm.nih.gov/pubmed/26655722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.675645
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