SDF-1alpha concentration dependent modulation of RhoA and Rac1 modifies breast cancer and stromal cells interaction

BACKGROUND: The interaction of SDF-1alpha with its receptor CXCR4 plays a role in the occurrence of distant metastasis in many solid tumors. This interaction increases migration from primary sites as well as homing at distant sites. METHODS: Here we investigated how SDF-1α could modulate both migrat...

Полное описание

Сохранить в:
Библиографические подробности
Опубликовано в: :BMC Cancer
Главные авторы: Pasquier, Jennifer, Abu-Kaoud, Nadine, Abdesselem, Houari, Madani, Aisha, Hoarau-Véchot, Jessica, Thawadi, Hamda Al., Vidal, Fabien, Couderc, Bettina, Favre, Gilles, Rafii, Arash
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2015
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4522077/
https://ncbi.nlm.nih.gov/pubmed/26231656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-015-1556-7
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы