SDF-1alpha concentration dependent modulation of RhoA and Rac1 modifies breast cancer and stromal cells interaction

BACKGROUND: The interaction of SDF-1alpha with its receptor CXCR4 plays a role in the occurrence of distant metastasis in many solid tumors. This interaction increases migration from primary sites as well as homing at distant sites. METHODS: Here we investigated how SDF-1α could modulate both migrat...

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Bibliographic Details
Published in:BMC Cancer
Main Authors: Pasquier, Jennifer, Abu-Kaoud, Nadine, Abdesselem, Houari, Madani, Aisha, Hoarau-Véchot, Jessica, Thawadi, Hamda Al., Vidal, Fabien, Couderc, Bettina, Favre, Gilles, Rafii, Arash
Format: Artigo
Language:Inglês
Published: BioMed Central 2015
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4522077/
https://ncbi.nlm.nih.gov/pubmed/26231656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-015-1556-7
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