SIRT1 promotes lipid metabolism and mitochondrial biogenesis in adipocytes and coordinates adipogenesis by targeting key enzymatic pathways

The NAD(+)-dependent deacetylase SIRT1 controls key metabolic functions by deacetylating target proteins and strategies that promote SIRT1 function such as SIRT1 overexpression or NAD(+) boosters alleviate metabolic complications. We previously reported that SIRT1-depletion in 3T3-L1 preadipocytes l...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Sci Rep
मुख्य लेखकों: Majeed, Yasser, Halabi, Najeeb, Madani, Aisha Y., Engelke, Rudolf, Bhagwat, Aditya M., Abdesselem, Houari, Agha, Maha V., Vakayil, Muneera, Courjaret, Raphael, Goswami, Neha, Hamidane, Hisham Ben, Elrayess, Mohamed A., Rafii, Arash, Graumann, Johannes, Schmidt, Frank, Mazloum, Nayef A.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Nature Publishing Group UK 2021
विषय:
Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC8046990/
https://ncbi.nlm.nih.gov/pubmed/33854178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-87759-x
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