Signal Transducer and Activator of Transcription 3 (STAT3) Suppresses STAT1/Interferon Signaling Pathway and Inflammation in Senescent Preadipocytes

Obesity promotes premature aging and dysfunction of white adipose tissue (WAT) through the accumulation of cellular senescence. The senescent cells burden in WAT has been linked to inflammation, insulin-resistance (IR), and type 2 diabetes (T2D). There is limited knowledge about molecular mechanisms...

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Vydáno v:Antioxidants (Basel)
Hlavní autoři: Madani, Aisha Y., Majeed, Yasser, Abdesselem, Houari B., Agha, Maha V., Vakayil, Muneera, Sukhun, Nour K. Al, Halabi, Najeeb M., Kumar, Pankaj, Hayat, Shahina, Elrayess, Mohamed A., Rafii, Arash, Suhre, Karsten, Mazloum, Nayef A.
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2021
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7927067/
https://ncbi.nlm.nih.gov/pubmed/33672392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antiox10020334
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