Signal Transducer and Activator of Transcription 3 (STAT3) Suppresses STAT1/Interferon Signaling Pathway and Inflammation in Senescent Preadipocytes

Obesity promotes premature aging and dysfunction of white adipose tissue (WAT) through the accumulation of cellular senescence. The senescent cells burden in WAT has been linked to inflammation, insulin-resistance (IR), and type 2 diabetes (T2D). There is limited knowledge about molecular mechanisms...

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Publicat a:Antioxidants (Basel)
Autors principals: Madani, Aisha Y., Majeed, Yasser, Abdesselem, Houari B., Agha, Maha V., Vakayil, Muneera, Sukhun, Nour K. Al, Halabi, Najeeb M., Kumar, Pankaj, Hayat, Shahina, Elrayess, Mohamed A., Rafii, Arash, Suhre, Karsten, Mazloum, Nayef A.
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2021
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7927067/
https://ncbi.nlm.nih.gov/pubmed/33672392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antiox10020334
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