Signal Transducer and Activator of Transcription 3 (STAT3) Suppresses STAT1/Interferon Signaling Pathway and Inflammation in Senescent Preadipocytes

Obesity promotes premature aging and dysfunction of white adipose tissue (WAT) through the accumulation of cellular senescence. The senescent cells burden in WAT has been linked to inflammation, insulin-resistance (IR), and type 2 diabetes (T2D). There is limited knowledge about molecular mechanisms...

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Detalhes bibliográficos
Publicado no:Antioxidants (Basel)
Main Authors: Madani, Aisha Y., Majeed, Yasser, Abdesselem, Houari B., Agha, Maha V., Vakayil, Muneera, Sukhun, Nour K. Al, Halabi, Najeeb M., Kumar, Pankaj, Hayat, Shahina, Elrayess, Mohamed A., Rafii, Arash, Suhre, Karsten, Mazloum, Nayef A.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7927067/
https://ncbi.nlm.nih.gov/pubmed/33672392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antiox10020334
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