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Differential Toxicity of Antibodies to the Prion Protein

Antibodies against the prion protein PrP(C) can antagonize prion replication and neuroinvasion, and therefore hold promise as possible therapeutics against prion diseases. However, the safety profile of such antibodies is controversial. It was originally reported that the monoclonal antibody D13 exh...

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Dades bibliogràfiques
Publicat a:PLoS Pathog
Autors principals: Reimann, Regina R., Sonati, Tiziana, Hornemann, Simone, Herrmann, Uli S., Arand, Michael, Hawke, Simon, Aguzzi, Adriano
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4731068/
https://ncbi.nlm.nih.gov/pubmed/26821311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005401
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