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Differential Toxicity of Antibodies to the Prion Protein

Antibodies against the prion protein PrP(C) can antagonize prion replication and neuroinvasion, and therefore hold promise as possible therapeutics against prion diseases. However, the safety profile of such antibodies is controversial. It was originally reported that the monoclonal antibody D13 exh...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:PLoS Pathog
Egile Nagusiak: Reimann, Regina R., Sonati, Tiziana, Hornemann, Simone, Herrmann, Uli S., Arand, Michael, Hawke, Simon, Aguzzi, Adriano
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2016
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4731068/
https://ncbi.nlm.nih.gov/pubmed/26821311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005401
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