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Differential Toxicity of Antibodies to the Prion Protein

Antibodies against the prion protein PrP(C) can antagonize prion replication and neuroinvasion, and therefore hold promise as possible therapeutics against prion diseases. However, the safety profile of such antibodies is controversial. It was originally reported that the monoclonal antibody D13 exh...

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Bibliografiska uppgifter
I publikationen:PLoS Pathog
Huvudupphovsmän: Reimann, Regina R., Sonati, Tiziana, Hornemann, Simone, Herrmann, Uli S., Arand, Michael, Hawke, Simon, Aguzzi, Adriano
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2016
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4731068/
https://ncbi.nlm.nih.gov/pubmed/26821311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005401
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