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Differential Toxicity of Antibodies to the Prion Protein

Antibodies against the prion protein PrP(C) can antagonize prion replication and neuroinvasion, and therefore hold promise as possible therapeutics against prion diseases. However, the safety profile of such antibodies is controversial. It was originally reported that the monoclonal antibody D13 exh...

詳細記述

保存先:
書誌詳細
出版年:PLoS Pathog
主要な著者: Reimann, Regina R., Sonati, Tiziana, Hornemann, Simone, Herrmann, Uli S., Arand, Michael, Hawke, Simon, Aguzzi, Adriano
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4731068/
https://ncbi.nlm.nih.gov/pubmed/26821311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005401
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