Susceptibility to renal carcinoma in the Eker rat involves a tumor suppressor gene on chromosome 10.
Germ-line mutations of tumor suppressor genes confer strong predisposition to tumor formation. In the rat, a form of dominantly inherited renal carcinoma (RC) results in multiple chromophobe cell tumors that resemble the human disease, and heterozygous carriers (RC/+) are highly susceptible to envir...
Sábháilte in:
| Foilsithe in: | Proc Natl Acad Sci U S A |
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| Príomhchruthaitheoirí: | , , , |
| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe / Cruthaithe: |
National Academy of Sciences
1993
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| Ábhair: | |
| Rochtain ar líne: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC47283/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8103600/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.17.8038 |
| Clibeanna: |
Níl clibeanna ann, Bí ar an gcéad duine le clib a chur leis an taifead seo!
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