Susceptibility to renal carcinoma in the Eker rat involves a tumor suppressor gene on chromosome 10.

Germ-line mutations of tumor suppressor genes confer strong predisposition to tumor formation. In the rat, a form of dominantly inherited renal carcinoma (RC) results in multiple chromophobe cell tumors that resemble the human disease, and heterozygous carriers (RC/+) are highly susceptible to envir...

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Bibliografske podrobnosti
Main Authors: Yeung, R S, Buetow, K H, Testa, J R, Knudson, A G
Format: Artigo
Jezik:Inglês
Izdano: 1993
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC47283/
https://ncbi.nlm.nih.gov/pubmed/8103600
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