Improved Automated Radiosynthesis of [(11)C]PBR28

Microglial activation is commonly identified by elevated levels of the 18 kDa translocator protein (TSPO) in response to several inflammatory processes. [(11)C]PBR28 is one of the most promising PET tracers to image TSPO in both human and non-human primates. In this study, we optimized the radiolabe...

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Bibliographic Details
Published in:Sci Pharm
Main Authors: Solingapuram Sai, Kiran Kumar, Gage, Don, Nader, Mike, Mach, Robert H., Mintz, Akiva
Format: Artigo
Language:Inglês
Published: The Austrian Journal of Pharmaceutical Sciences 2015
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4727796/
https://ncbi.nlm.nih.gov/pubmed/26839827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3797/scipharm.1505-06
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