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DNA supercoiling, a critical signal regulating the basal expression of the lac operon in Escherichia coli
Escherichia coli lac repressor (LacI) is a paradigmatic transcriptional factor that controls the expression of lacZYA in the lac operon. This tetrameric protein specifically binds to the O1, O2 and O3 operators of the lac operon and forms a DNA loop to repress transcription from the adjacent lac pro...
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| Publié dans: | Sci Rep |
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| Auteurs principaux: | , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group
2016
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4725879/ https://ncbi.nlm.nih.gov/pubmed/26763930 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep19243 |
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